The Development Of Clotrimazole Muco-Adhesive Films For Denture Stomatitis Treatment
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Rubatex Neoprene 178
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Rubatex Pipe Faculty of Pharmacy
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Rubatex Pipe Insulation The Development of Clotrimazole Muco-adhesive Films for Denture Stomatitis
treatment (NO. 484)
Therefore, the development of safer, more convenient, and more effective treatments for acne is highly desirable. Treatment with various lasers has been reported to improve acne. NEw research evaluated the clinical efficacy of a type of laser treatment, pulsed dye laser therapy, for the treatment of acne. The study was a randomized, controlled, clinical trial that included 40 patients aged 13 years or older with facial acne.
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Rubatex 180 Fs Mansuang Wuthi-udomlert1, Pimolpan Pithayanukul2, Woranun Buajeeb3 and Nongluck Satitkarn 2
Rubatex 1800 1Department of Microbiology, 2Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand. 3Department of Microbiology, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Rubatex 320 Key words : clotrimazole, muco-adhesive films, denture stomatitis
Rubatex 373 Two percent clotrimazole muco-adhesive films were developed in this study for the purpose of long acting denture stomatitis treatment in denture wearing patients. The films were prepared by film casting method using hydroxypropylmethyl cellulose and polyethylene oxide as the muco-adhesive materials. Various properties of the film were studied: drug content uniformity, adhesive durations both in vitro and in vivo studies, in vitro effectiveness of clotrimazole film against Candida albicans by viable cell count method, and clinical evaluation in denture wearing patients.
Rubatex Rubber It was found that clotrimazole muco-adhesive films were in the form of long acting dosage form. The adhesive durations were in the range between 4-8 hours or more depending on the type of polymer used. The films were effective in destroying fungal micro-organism in denture stomatitis patients with improvement in clinical signs after the end of the treatment periods.
Rubatex Tape (Presented at Millennial World Congress of Pharmaceutical Sciences, Moscone Center, San Francisco, California, USA. 16-20 April 2000 : 120)
Felpro Gaskets Activity of lyophilized Sapindus extract against 216 clinical fungal Isolates (NO. 485)
Poly Hunting Feeders Mansuang Wuthi-udomlert1, Omboon Luanratana2 and Pankorn Imwidthaya3
Shoreline 13171 17 Neoprene 1Department of Microbiology, 2Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Sri Ayudthaya Rd., Rajthevi, Bangkok 10400, Thailand. 3Department of Microbiology, Faculty of Medicine, Mahidol University Siriraj Hospital, Bangkoknoi District, Bangkok 10700, Thailand.
Neoprene Pads Key words : Lyophilized Sapindus extract, dermatophytes & Candida albicans, antifungal activity
Neoprene Seat Covers Small pieces of dry pericarp of Sapindus sp. were macerated in distilled water for 24 hrs. After filtration, the aqueous crude extract was aliquoted and lyophilized, yielding 18.3% powder. By agar disc diffusion method, the powdered extract was tested for its inhibition efficacy against 216 clinical strains of fungi isolated from scalp and skin of patients attending Department of Dermatology, Siriraj Hospital, Bangkok, Thailand. It was found that the extract (20 mg/disc) inhibited 72 strains of dermatophytes with the average inhibition zone of 27.55 mm compared to 41.56 mm from ketoconazole (100 mcg/disc), which was used as reference drug. The activity of the extract against 65 strains of Candida albicans, 47 Cryptococcus neoformans, and 32 Pityrosporum spp. expressed average inhibition zone diameters of 14.54, 16.54, and 16.69 mm respectively, compared to 22.63, 43.37, and 43.26 mm from ketoconazole. Thus, all activities of the powdered extract on the tested fungi were significantly different from ketoconazoles. The susceptibility of dermatophytes and all yeasts to powdered extract in this study was also significantly different (p<0.01).
Rubber Manufacturer (Presented at 3rd International Congress on Phytomedicine, October 11-13, 2000, Munich, Germany.) (Phytomedicine Vol 7 (2000) Suppl. II : 87)
Foam Insulation Antibacterial and antifungal activi-ties of curcuminoids from Curcumalonga grown in
Thailand (NO. 486)
Industrial Petroleum Products Wandee Gritsanapan1, Mansuang Wuthi-udomlert2 and Wanida Caichompoo1
Petroleum Refiner 1Department of Pharmacognosy, 2Department of Microbiology, Faculty of Pharmacy, Mahidol University, Sri Ayudthaya Rd., Rajthevi, Bangkok 10400, Thailand.
Petroleum Products Key words : Curcuma longa, antifungal activity, medicinal plant
Rubatex International Curcuma longa Linn. (Zingiberaceae) is a medicinal plant which its rhizome is used in Thailand for peptic ulcer and wound treatments, carminatives, anti-inflammatory agent and antifungal for skin diseases. Turmeric oil (7.02 % v/w) was extracted from dried rhizome while crude curcuminoids (6.95 %w/w) which comprised curcumin (11.6 %), demethoxycurcumin (10.32 %) and bisdemethoxycurcumin (10.77 %) seperated by preparative TLC were obtained. Ethanol extract, turmeric oil, crude curcuminoids, curcumin, demethoxycurcumin and bisdemethoxycurcumin were tested for antifungal and antibacterial activities using agar diffusion method against 29 clinical strains of dermatophytes, 13 standard and 8 laboratory strains of bacteria. It was found that turmeric oil exhibited the best inhibiting activity against dermatophytes (26.1-46.0 mm) while crude ethanol extract showed inhibition zone range of 6.1-26.0 mm. There was no inhibition against all tested dermatophytes by crude curcuminoids while curcumin, demethoxycurcumin and bisdemethoxycurcumin yielded low activities with diameters ranging from 6.1 to 16.0 mm. With 200 mg ketoconazole, the activity of the standard was similar to the oil but was significantly different from those curcuminoid compounds and crude ethanol extract (p < 0.1). By broth dilution method, turmeric oil showed the MICs at 7.8 mg/ml. For bacteria, all extracts showed unsatisfactory activities except Streptococcus pyogenes (17.0 mm).
Rubatex Msds (Presented at 3rd International Congress on Phytomedicine, October 11-13,2000, Munich, Germany) (Phytomedicine Vol 7(2000)
Rubatex Pipe Insulation Susceptibility of clinical isolate Pityrosporum spp. to lyophilized Sapindus extract
(no. 487)
Rubatex 180 Fs Mansuang Wuthi-udomlert1, Pankorn Imwidthaya2 and Omboon Luanratana3
Rubatex 1800 1Department of Microbiology, Faculty of Pharmacy, Mahidol University, Sri Ayudthaya Rd., Rajthevi, Bangkok 10400, Thai-
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